Welcome to a new Event Series by Epicenter Amsterdam and Isabel Shestopal.What does leadership mean when some of your “team members” are autonomous, some are tools, and some are human?

AI is changing more than how work gets done. It is changing how decisions are made, how teams operate, and what it means to lead.

As AI systems take on more responsibility, leaders face questions that cannot be answered by technology alone. How do you motivate and develop people when parts of their work are handled by AI? Which decisions should remain human? Who is accountable when people and autonomous systems share responsibility? And how do we protect trust, judgment, creativity, and connection as teams become increasingly automated?

Leading Minds and Machines is the first installment of AI at Work, a new event series hosted by Isabel Shestopal and Epicenter.

The event brings together perspectives from leadership, organizational psychology, and companies already learning how to operate with AI. We will explore the new capabilities leaders need and the practical choices organizations are beginning to face.

The conversation will examine:

  • How to lead teams working alongside AI agents

  • Which responsibilities can be delegated to AI and which should remain human

  • How accountability changes when decisions are shared with autonomous systems

  • How leaders can maintain trust, motivation, and connection

  • Which leadership capabilities will matter most over the next five years

Speaker lineup to be announced.